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The histone acetyltransferase MOF activates hypothalamic polysialylation to prevent diet-induced obesity in mice
Overfeeding causes rapid synaptic remodeling in hypothalamus feeding circuits. Polysialylation of cell surface molecules is a key step in this neuronal rewiring and allows normalization of food intake. Here we examined the role of hypothalamic polysialylation in the long-term maintenance of body wei...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142401/ https://ncbi.nlm.nih.gov/pubmed/25161885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.05.006 |
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