The histone acetyltransferase MOF activates hypothalamic polysialylation to prevent diet-induced obesity in mice

Overfeeding causes rapid synaptic remodeling in hypothalamus feeding circuits. Polysialylation of cell surface molecules is a key step in this neuronal rewiring and allows normalization of food intake. Here we examined the role of hypothalamic polysialylation in the long-term maintenance of body wei...

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Hlavní autoři: Brenachot, Xavier, Rigault, Caroline, Nédélec, Emmanuelle, Laderrière, Amélie, Khanam, Tasneem, Gouazé, Alexandra, Chaudy, Sylvie, Lemoine, Aleth, Datiche, Frédérique, Gascuel, Jean, Pénicaud, Luc, Benani, Alexandre
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142401/
https://ncbi.nlm.nih.gov/pubmed/25161885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.05.006
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