Donor Haplotype B of NK KIR Receptor Reduces the Relapse Risk in HLA-Identical Sibling Hematopoietic Stem Cell Transplantation of AML Patients

Successful allogeneic hematopoietic stem cell transplantation (HSCT) depends not only on good HLA match but also on T-cell mediated graft-versus-leukemia (GvL) effect. Natural killer (NK) cells are able to kill malignant cells by receiving activation signal from the killer-cell immunoglobulin-like r...

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Detalhes bibliográficos
Main Authors: Impola, Ulla, Turpeinen, Hannu, Alakulppi, Noora, Linjama, Tiina, Volin, Liisa, Niittyvuopio, Riitta, Partanen, Jukka, Koskela, Satu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142321/
https://ncbi.nlm.nih.gov/pubmed/25202311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00405
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