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Costs and benefits of mutational robustness in RNA viruses

The accumulation of mutations in RNA viruses is thought to facilitate rapid adaptation to changes in the environment. However, most mutations have deleterious effects on fitness, especially so for viruses. Thus, tolerance to mutations should determine the nature and extent of genetic diversity that...

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Main Authors: Stern, Adi, Bianco, Simone, TeYeh, Ming, Wright, Caroline, Butcher, Kristin, Tang, Chao, Nielsen, Rasmus, Andino, Raul
格式: Artigo
語言:Inglês
出版: 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142091/
https://ncbi.nlm.nih.gov/pubmed/25127138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.011
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