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Costs and benefits of mutational robustness in RNA viruses

The accumulation of mutations in RNA viruses is thought to facilitate rapid adaptation to changes in the environment. However, most mutations have deleterious effects on fitness, especially so for viruses. Thus, tolerance to mutations should determine the nature and extent of genetic diversity that...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Stern, Adi, Bianco, Simone, TeYeh, Ming, Wright, Caroline, Butcher, Kristin, Tang, Chao, Nielsen, Rasmus, Andino, Raul
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142091/
https://ncbi.nlm.nih.gov/pubmed/25127138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.011
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