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Costs and benefits of mutational robustness in RNA viruses

The accumulation of mutations in RNA viruses is thought to facilitate rapid adaptation to changes in the environment. However, most mutations have deleterious effects on fitness, especially so for viruses. Thus, tolerance to mutations should determine the nature and extent of genetic diversity that...

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Bibliographic Details
Main Authors: Stern, Adi, Bianco, Simone, TeYeh, Ming, Wright, Caroline, Butcher, Kristin, Tang, Chao, Nielsen, Rasmus, Andino, Raul
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142091/
https://ncbi.nlm.nih.gov/pubmed/25127138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.011
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