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Costs and benefits of mutational robustness in RNA viruses

The accumulation of mutations in RNA viruses is thought to facilitate rapid adaptation to changes in the environment. However, most mutations have deleterious effects on fitness, especially so for viruses. Thus, tolerance to mutations should determine the nature and extent of genetic diversity that...

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Библиографические подробности
Главные авторы: Stern, Adi, Bianco, Simone, TeYeh, Ming, Wright, Caroline, Butcher, Kristin, Tang, Chao, Nielsen, Rasmus, Andino, Raul
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142091/
https://ncbi.nlm.nih.gov/pubmed/25127138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.011
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