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Mutational Landscape of Candidate Genes in Familial Prostate Cancer

BACKGROUND: Family history is a major risk factor for prostate cancer (PCa), suggesting a genetic component to the disease. However, traditional linkage and association studies have failed to fully elucidate the underlying genetic basis of familial PCa. METHODS: Here we use a candidate gene approach...

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Detalhes bibliográficos
Main Authors: Johnson, Anna M., Zuhlke, Kimberly A., Plotts, Chris, McDonnell, Shannon K., Middha, Sumit, Riska, Shaun M., Thibodeau, Stephen N., Douglas, Julie A., Cooney, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142071/
https://ncbi.nlm.nih.gov/pubmed/25111073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22849
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