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Treating ALK positive lung cancer: Early successes and coming challenges
Rearrangements of the anaplastic lymphoma kinase (ALK) gene occur infrequently in non-small cell lung cancer (NSCLC), but provide an important paradigm for oncogene-directed therapy in this disease. Crizotinib, an orally bioavailable inhibitor of ALK, provides significant benefit for patients with A...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142046/ https://ncbi.nlm.nih.gov/pubmed/22473102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2012.43 |
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