Reproduction and sera embryotoxicity after immunization of monkeys with the laminin peptides YIGSR, RGD, and IKVAV.

Monkeys with excellent reproductive histories were immunized with the laminin peptides YIGSR, RGD, IKVAV, and YD, a control sequence with no known biological function. Sera from the YIGSR-immunized monkey became toxic, causing neural tube defects in whole rat embryo cultures, and this monkey experie...

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Main Authors: Chambers, B J, Klein, N W, Conrad, S H, Ruppenthal, G C, Sackett, G P, Weeks, B S, Kleinman, H K
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41420/
https://ncbi.nlm.nih.gov/pubmed/7624326
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