Sialic Acid Metabolic Engineering: A Potential Strategy for the Neuroblastoma Therapy

BACKGROUND: Sialic acids (Sia) represent negative-charged terminal sugars on most glycoproteins and glycolipids on the cell surface of vertebrates. Aberrant expression of tumor associated sialylated carbohydrate epitopes significantly increases during onset of cancer. Since Sia contribute towards ce...

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Main Authors: Gnanapragassam, Vinayaga S., Bork, Kaya, Galuska, Christina E., Galuska, Sebastian P., Glanz, Dagobert, Nagasundaram, Manimozhi, Bache, Matthias, Vordermark, Dirk, Kohla, Guido, Kannicht, Christoph, Schauer, Roland, Horstkorte, Rüdiger
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141789/
https://ncbi.nlm.nih.gov/pubmed/25148252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105403
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