Sialic Acid Metabolic Engineering: A Potential Strategy for the Neuroblastoma Therapy

BACKGROUND: Sialic acids (Sia) represent negative-charged terminal sugars on most glycoproteins and glycolipids on the cell surface of vertebrates. Aberrant expression of tumor associated sialylated carbohydrate epitopes significantly increases during onset of cancer. Since Sia contribute towards ce...

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Hlavní autoři: Gnanapragassam, Vinayaga S., Bork, Kaya, Galuska, Christina E., Galuska, Sebastian P., Glanz, Dagobert, Nagasundaram, Manimozhi, Bache, Matthias, Vordermark, Dirk, Kohla, Guido, Kannicht, Christoph, Schauer, Roland, Horstkorte, Rüdiger
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141789/
https://ncbi.nlm.nih.gov/pubmed/25148252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105403
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