Sialic Acid Metabolic Engineering: A Potential Strategy for the Neuroblastoma Therapy

BACKGROUND: Sialic acids (Sia) represent negative-charged terminal sugars on most glycoproteins and glycolipids on the cell surface of vertebrates. Aberrant expression of tumor associated sialylated carbohydrate epitopes significantly increases during onset of cancer. Since Sia contribute towards ce...

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Autors principals: Gnanapragassam, Vinayaga S., Bork, Kaya, Galuska, Christina E., Galuska, Sebastian P., Glanz, Dagobert, Nagasundaram, Manimozhi, Bache, Matthias, Vordermark, Dirk, Kohla, Guido, Kannicht, Christoph, Schauer, Roland, Horstkorte, Rüdiger
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141789/
https://ncbi.nlm.nih.gov/pubmed/25148252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105403
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