Sialic Acid Metabolic Engineering: A Potential Strategy for the Neuroblastoma Therapy

BACKGROUND: Sialic acids (Sia) represent negative-charged terminal sugars on most glycoproteins and glycolipids on the cell surface of vertebrates. Aberrant expression of tumor associated sialylated carbohydrate epitopes significantly increases during onset of cancer. Since Sia contribute towards ce...

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Detalhes bibliográficos
Main Authors: Gnanapragassam, Vinayaga S., Bork, Kaya, Galuska, Christina E., Galuska, Sebastian P., Glanz, Dagobert, Nagasundaram, Manimozhi, Bache, Matthias, Vordermark, Dirk, Kohla, Guido, Kannicht, Christoph, Schauer, Roland, Horstkorte, Rüdiger
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141789/
https://ncbi.nlm.nih.gov/pubmed/25148252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105403
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