Contractile Force Is Enhanced in Aortas from Pendrin Null Mice Due to Stimulation of Angiotensin II-Dependent Signaling

Pendrin is a Cl(−)/HCO(3) (−) exchanger expressed in the apical regions of renal intercalated cells. Following pendrin gene ablation, blood pressure falls, in part, from reduced renal NaCl absorption. We asked if pendrin is expressed in vascular tissue and if the lower blood pressure observed in pen...

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Autores principales: Sutliff, Roy L., Walp, Erik R., Kim, Young Hee, Walker, Lori A., El-Ali, Alexander M., Ma, Jing, Bonsall, Robert, Ramosevac, Semra, Eaton, Douglas C., Verlander, Jill W., Hansen, Laura, Gleason, Rudolph L. Jr., Pham, Truyen D., Hong, Seongun, Pech, Vladimir, Wall, Susan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141771/
https://ncbi.nlm.nih.gov/pubmed/25148130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105101
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