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Approximate and Exact Tests of Hardy-Weinberg Equilibrium Using Uncertain Genotypes

Testing for Hardy-Weinberg equilibrium (HWE) is commonly used as a quality control filter in genome-wide scans for markers with experimentally determined genotypes. In contrast, for markers with imputed genotypes, there are post-imputation metrics of quality that can be used as screens but there are...

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Bibliografske podrobnosti
Glavni avtor: Shriner, Daniel
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141651/
https://ncbi.nlm.nih.gov/pubmed/21922537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20612
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