A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid utilization

Food intake increases the activity of hepatic de novo lipogenesis, which mediates the conversion of glucose to fats for storage or utilization. In mice, this program follows a circadian rhythm that peaks with nocturnal feeding(1,2) and is repressed by Rev-erbα/β and an HDAC3-containing complex(3–5)...

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Detalhes bibliográficos
Main Authors: Liu, Sihao, Brown, Jonathan D., Stanya, Kristopher J., Homan, Edwin, Leidl, Mathias, Inouye, Karen, Bhargava, Prerna, Gangl, Matthew R., Dai, Lingling, Hatano, Ben, Hotamisligil, Gökhan S., Saghatelian, Alan, Plutzky, Jorge, Lee, Chih-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141623/
https://ncbi.nlm.nih.gov/pubmed/24153306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12710
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