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Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways

Parasitic worms express host-like glycans to attenuate the immune response of human hosts. The therapeutic potential of this immunomodulatory mechanism in controlling metabolic dysfunction associated with chronic inflammation remains unexplored. We demonstrate here that administration of Lacto-N-fuc...

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Autori principali: Bhargava, Prerna, Li, Changlin, Stanya, Kristopher J., Jacobi, David, Dai, Lingling, Liu, Sihao, Gangl, Matthew R., Harn, Donald A., Lee, Chih-Hao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493877/
https://ncbi.nlm.nih.gov/pubmed/23104131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2962
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