Tacrolimus/sirolimus vs tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic HCT

Grades 2-4 acute graft-versus-host disease (GVHD) occurs in approximately 35% of matched, related donor (MRD) allogeneic hematopoietic cell transplantation (HCT) recipients. We sought to determine if the combination of tacrolimus and sirolimus (Tac/Sir) was more effective than tacrolimus and methotr...

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Autors principals: Cutler, Corey, Logan, Brent, Nakamura, Ryotaro, Johnston, Laura, Choi, Sung, Porter, David, Hogan, William J., Pasquini, Marcelo, MacMillan, Margaret L., Hsu, Jack W., Waller, Edmund K., Grupp, Stephan, McCarthy, Philip, Wu, Juan, Hu, Zhen-Huan, Carter, Shelly L., Horowitz, Mary M., Antin, Joseph H.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Transplantation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141519/
https://ncbi.nlm.nih.gov/pubmed/24982504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-567164
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