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Asparaginase allergies: it’s all in the genes

In this issue of Blood, Fernandez et al demonstrate that human leukocyte antigen (HLA) DRB1 alleles confer high-affinity binding to asparaginase epitopes, leading to higher frequency of allergic reactions.(1) The authors initially examined HLA data from European ancestry patients enrolled onto St. J...

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Bibliografische gegevens
Hoofdauteur: Wetzler, Meir
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141504/
https://ncbi.nlm.nih.gov/pubmed/25147374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-585919
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