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Temporospatial Coordination of Meiotic DNA Replication and Recombination via DDK Recruitment to Replisomes

It has been long appreciated that during meiosis DNA replication is coordinated with the subsequent formation of the double-strand breaks (DSBs) that initiate recombination, but a mechanistic understanding of this process was elusive. We now show that in yeast the replisome-associated components Tof...

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Detalhes bibliográficos
Main Authors: Murakami, Hajime, Keeney, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141489/
https://ncbi.nlm.nih.gov/pubmed/25126790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.028
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