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Temporospatial Coordination of Meiotic DNA Replication and Recombination via DDK Recruitment to Replisomes

It has been long appreciated that during meiosis DNA replication is coordinated with the subsequent formation of the double-strand breaks (DSBs) that initiate recombination, but a mechanistic understanding of this process was elusive. We now show that in yeast the replisome-associated components Tof...

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Bibliografiske detaljer
Main Authors: Murakami, Hajime, Keeney, Scott
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141489/
https://ncbi.nlm.nih.gov/pubmed/25126790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.028
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