Parp Inhibition Prevents Ten-Eleven Translocase Enzyme Activation and Hyperglycemia-Induced DNA Demethylation

Studies from human cells, rats, and zebrafish have documented that hyperglycemia (HG) induces the demethylation of specific cytosines throughout the genome. We previously documented that a subset of these changes become permanent and may provide, in part, a mechanism for the persistence of complicat...

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Detaylı Bibliyografya
Asıl Yazarlar: Dhliwayo, Nyembezi, Sarras, Michael P., Luczkowski, Ernest, Mason, Samantha M., Intine, Robert V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2014
Konular:
Complications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141369/
https://ncbi.nlm.nih.gov/pubmed/24722243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1916
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