In silico analysis identifies novel restriction enzyme combinations that expand reduced representation bisulfite sequencing CpG coverage

BACKGROUND: Epigenetics is the study of gene expression changes that are not caused by changes in the deoxyribonucleic acid (DNA) sequence. DNA methylation is an epigenetic mark occurring in C–phosphate–G sites (CpGs) that leads to local or regional gene expression changes. Reduced-representation bi...

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Bibliographic Details
Main Authors: Martinez-Arguelles, Daniel B, Lee, Sunghoon, Papadopoulos, Vassilios
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141122/
https://ncbi.nlm.nih.gov/pubmed/25127888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-534
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