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γδ T cells restrain extrathymic development of Foxp3+ inducible regulatory T cells via IFNγ

Inducible regulatory T cells (iTregs) generated from antigen-stimulated naïve CD4 T cells in the periphery play an important role in regulating immune responses. TGFβ is a key cytokine that promotes this conversion process; however, how this process is regulated in vivo remains unclear. Here we repo...

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Hlavní autoři: Visperas, Anabelle, Shen, Bo, Min, Booki
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141022/
https://ncbi.nlm.nih.gov/pubmed/24799116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344331
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