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A Multi-Compartment Mathematical Model of Cancer Stem Cell Driven Tumor Growth Dynamics

Tumors are appreciated to be an intrinsically heterogeneous population of cells with varying proliferation capacities and tumorigenic potentials. As a central tenet of the so-called cancer stem cell hypothesis, most cancer cells have only a limited lifespan and thus cannot initiate or re-initiate tu...

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Detalhes bibliográficos
Main Authors: Weekes, Suzanne L., Barker, Brian, Bober, Sarah, Cisneros, Karina, Cline, Justina, Thompson, Amanda, Hlatky, Lynn, Hahnfeldt, Philip, Enderling, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140966/
https://ncbi.nlm.nih.gov/pubmed/24840956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-014-9976-0
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