New Role for Kruppel-like Factor 14 as a Transcriptional Activator Involved in the Generation of Signaling Lipids

Sphingosine kinase 1 (SK1) is an FGF-inducible gene responsible for generation of sphingosine-1-phosphate, a critical lipid signaling molecule implicated in diverse endothelial cell functions. In this study, we identified SK1 as a target of the canonical FGF2/FGF receptor 1 activation pathway in end...

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Detalhes bibliográficos
Main Authors: de Assuncao, Thiago M., Lomberk, Gwen, Cao, Sheng, Yaqoob, Usman, Mathison, Angela, Simonetto, Douglas A., Huebert, Robert C., Urrutia, Raul A., Shah, Vijay H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140934/
https://ncbi.nlm.nih.gov/pubmed/24759103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544346
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