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Small RNA Sequence Analysis of Adenovirus VA RNA-Derived MiRNAs Reveals an Unexpected Serotype-Specific Difference in Structure and Abundance

Human adenoviruses (HAds) encode for one or two highly abundant virus-associated RNAs, designated VA RNAI and VA RNAII, which fold into stable hairpin structures resembling miRNA precursors. Here we show that the terminal stem of the VA RNAs originating from Ad4, Ad5, Ad11 and Ad37, all undergo Dice...

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Autors principals: Kamel, Wael, Segerman, Bo, Punga, Tanel, Akusjärvi, Göran
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140831/
https://ncbi.nlm.nih.gov/pubmed/25144466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105746
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