Poly(ADP-Ribose) Polymerase 1 (PARP1) Overexpression in Human Breast Cancer Stem Cells and Resistance to Olaparib

BACKGROUND: Breast cancer stem cells (BCSCs) have been recognized as playing a major role in various aspects of breast cancer biology. To identify specific biomarkers of BCSCs, we have performed comparative proteomics of BCSC-enriched and mature cancer cell populations from the human breast cancer c...

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Huvudupphovsmän: Gilabert, Marine, Launay, Simon, Ginestier, Christophe, Bertucci, François, Audebert, Stéphane, Pophillat, Mathieu, Toiron, Yves, Baudelet, Emilie, Finetti, Pascal, Noguchi, Tetsuro, Sobol, Hagay, Birnbaum, Daniel, Borg, Jean-Paul, Charafe-Jauffret, Emmanuelle, Gonçalves, Anthony
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140711/
https://ncbi.nlm.nih.gov/pubmed/25144364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104302
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