High-Level Microsatellite Instability in Appendiceal Carcinomas

High-level microsatellite instability (MSI-high) is found in approximately 15% of all colorectal adenocarcinomas (CRCs) and in at least 20% of right-sided cancers. It is most commonly due to somatic hypermethylation of the MLH1 gene promoter region, with familial cases (Lynch syndrome) representing...

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Main Authors: Taggart, Melissa W., Galbincea, John, Mansfield, Paul F., Fournier, Keith F., Royal, Richard E., Overman, Michael J., Rashid, Asif, Abraham, Susan C.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140656/
https://ncbi.nlm.nih.gov/pubmed/23648460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0b013e318282649b
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