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High-Level Microsatellite Instability in Appendiceal Carcinomas
High-level microsatellite instability (MSI-high) is found in approximately 15% of all colorectal adenocarcinomas (CRCs) and in at least 20% of right-sided cancers. It is most commonly due to somatic hypermethylation of the MLH1 gene promoter region, with familial cases (Lynch syndrome) representing...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140656/ https://ncbi.nlm.nih.gov/pubmed/23648460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0b013e318282649b |
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