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Synthesis of a FTO Inhibitor with Anticonvulsant Activity
[Image: see text] We describe the rationale for and the synthesis of a new class of compounds utilizing a modular approach that are designed to mimic ascorbic acid and to inhibit 2-oxoglutarate-dependent hydroxylases. Preliminary characterization of one of these compounds indicates in vivo anticonvu...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140589/ https://ncbi.nlm.nih.gov/pubmed/24834807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500042t |
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