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Expression of an expanded CGG-repeat RNA in a single pair of primary sensory neurons impairs olfactory adaptation in Caenorhabditis elegans
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a severe neurodegenerative disorder that affects carriers of premutation CGG-repeat expansion alleles of the fragile X mental retardation 1 (FMR1) gene; current evidence supports a causal role of the expanded CGG repeat within the FMR1 mRNA in t...
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Auteurs principaux: | , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Oxford University Press
2014
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140470/ https://ncbi.nlm.nih.gov/pubmed/24821701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu210 |
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