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C. elegans orthologs MUT-7/CeWRN-1 of Werner syndrome protein regulate neuronal plasticity

Caenorhabditis elegans expresses human Werner syndrome protein (WRN) orthologs as two distinct proteins: MUT-7, with a 3′−5′ exonuclease domain, and CeWRN-1, with helicase domains. How these domains cooperate remains unclear. Here, we demonstrate the different contributions of MUT-7 and CeWRN-1 to 2...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hsu, Tsung-Yuan, Zhang, Bo, L'Etoile, Noelle D, Juang, Bi-Tzen
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946423/
https://ncbi.nlm.nih.gov/pubmed/33646120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62449
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