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Bronchoalveolar lavage neuregulin-1 is elevated in acute lung injury and correlates with inflammation

Shedding of neuregulin (NRG)-1 from the pulmonary epithelium leads to activation of the epithelial human epidermal growth factor receptor (HER)2 receptor, increased pulmonary epithelial permeability and acute lung injury (ALI). We sought to determine whether NRG-1 was detectable and elevated in bron...

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Bibliografiska uppgifter
Huvudupphovsmän: Finigan, James H., Mishra, Rangnath, Vasu, Vihas T., Silveira, Lori J., Nethery, David E., Standiford, Theodore J., Burnham, Ellen L., Moss, Marc, Kern, Jeffrey A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140244/
https://ncbi.nlm.nih.gov/pubmed/22599357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00004912
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