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Bronchoalveolar lavage neuregulin-1 is elevated in acute lung injury and correlates with inflammation

Shedding of neuregulin (NRG)-1 from the pulmonary epithelium leads to activation of the epithelial human epidermal growth factor receptor (HER)2 receptor, increased pulmonary epithelial permeability and acute lung injury (ALI). We sought to determine whether NRG-1 was detectable and elevated in bron...

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Detalhes bibliográficos
Main Authors: Finigan, James H., Mishra, Rangnath, Vasu, Vihas T., Silveira, Lori J., Nethery, David E., Standiford, Theodore J., Burnham, Ellen L., Moss, Marc, Kern, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140244/
https://ncbi.nlm.nih.gov/pubmed/22599357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00004912
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