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Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation

INTRODUCTION: Nanosized particles may enable therapeutic modulation of immune responses by targeting dendritic cell (DC) networks in accessible organs such as the lung. To date, however, the effects of nanoparticles on DC function and downstream immune responses remain poorly understood. METHODS: Bo...

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Библиографические подробности
Главные авторы: Seydoux, Emilie, Rothen-Rutishauser, Barbara, Nita, Izabela M, Balog, Sandor, Gazdhar, Amiq, Stumbles, Philip A, Petri-Fink, Alke, Blank, Fabian, von Garnier, Christophe
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140235/
https://ncbi.nlm.nih.gov/pubmed/25152619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S64353
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