Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation

INTRODUCTION: Nanosized particles may enable therapeutic modulation of immune responses by targeting dendritic cell (DC) networks in accessible organs such as the lung. To date, however, the effects of nanoparticles on DC function and downstream immune responses remain poorly understood. METHODS: Bo...

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Main Authors: Seydoux, Emilie, Rothen-Rutishauser, Barbara, Nita, Izabela M, Balog, Sandor, Gazdhar, Amiq, Stumbles, Philip A, Petri-Fink, Alke, Blank, Fabian, von Garnier, Christophe
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2014
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140235/
https://ncbi.nlm.nih.gov/pubmed/25152619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S64353
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