Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation

INTRODUCTION: Nanosized particles may enable therapeutic modulation of immune responses by targeting dendritic cell (DC) networks in accessible organs such as the lung. To date, however, the effects of nanoparticles on DC function and downstream immune responses remain poorly understood. METHODS: Bo...

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Detalhes bibliográficos
Main Authors: Seydoux, Emilie, Rothen-Rutishauser, Barbara, Nita, Izabela M, Balog, Sandor, Gazdhar, Amiq, Stumbles, Philip A, Petri-Fink, Alke, Blank, Fabian, von Garnier, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140235/
https://ncbi.nlm.nih.gov/pubmed/25152619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S64353
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