Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation

INTRODUCTION: Nanosized particles may enable therapeutic modulation of immune responses by targeting dendritic cell (DC) networks in accessible organs such as the lung. To date, however, the effects of nanoparticles on DC function and downstream immune responses remain poorly understood. METHODS: Bo...

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Autors principals: Seydoux, Emilie, Rothen-Rutishauser, Barbara, Nita, Izabela M, Balog, Sandor, Gazdhar, Amiq, Stumbles, Philip A, Petri-Fink, Alke, Blank, Fabian, von Garnier, Christophe
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140235/
https://ncbi.nlm.nih.gov/pubmed/25152619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S64353
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