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Novel and Functional DNA Sequence Variants within the GATA6 Gene Promoter in Ventricular Septal Defects

Congenital heart disease (CHD) is the most common birth defect in humans. Genetic causes and underlying molecular mechanisms for isolated CHD remain largely unknown. Studies have demonstrated that GATA transcription factor 6 (GATA6) plays an essential role in the heart development. Mutations in GATA...

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Detalhes bibliográficos
Main Authors: Li, Chunyu, Li, Xianke, Pang, Shuchao, Chen, Wei, Qin, Xianyun, Huang, Wenhui, Zeng, Changqing, Yan, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139867/
https://ncbi.nlm.nih.gov/pubmed/25036032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150712677
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