Novel and Functional DNA Sequence Variants within the GATA6 Gene Promoter in Ventricular Septal Defects

Congenital heart disease (CHD) is the most common birth defect in humans. Genetic causes and underlying molecular mechanisms for isolated CHD remain largely unknown. Studies have demonstrated that GATA transcription factor 6 (GATA6) plays an essential role in the heart development. Mutations in GATA...

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Main Authors: Li, Chunyu, Li, Xianke, Pang, Shuchao, Chen, Wei, Qin, Xianyun, Huang, Wenhui, Zeng, Changqing, Yan, Bo
Format: Artigo
Language:Inglês
Published: MDPI 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139867/
https://ncbi.nlm.nih.gov/pubmed/25036032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150712677
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