Critical Role for the Protons in FRTL-5 Thyroid Cells: Nuclear Sphingomyelinase Induced-Damage

Proliferating thyroid cells are more sensitive to UV-C radiations than quiescent cells. The effect is mediated by nuclear phosphatidylcholine and sphingomyelin metabolism. It was demonstrated that proton beams arrest cell growth and stimulate apoptosis but until now there have been no indications in...

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Main Authors: Albi, Elisabetta, Perrella, Giuseppina, Lazzarini, Andrea, Cataldi, Samuela, Lazzarini, Remo, Floridi, Alessandro, Ambesi-Impiombato, Francesco Saverio, Curcio, Francesco
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139799/
https://ncbi.nlm.nih.gov/pubmed/24979136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150711555
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