Critical Role for the Protons in FRTL-5 Thyroid Cells: Nuclear Sphingomyelinase Induced-Damage

Proliferating thyroid cells are more sensitive to UV-C radiations than quiescent cells. The effect is mediated by nuclear phosphatidylcholine and sphingomyelin metabolism. It was demonstrated that proton beams arrest cell growth and stimulate apoptosis but until now there have been no indications in...

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Bibliografiske detaljer
Main Authors: Albi, Elisabetta, Perrella, Giuseppina, Lazzarini, Andrea, Cataldi, Samuela, Lazzarini, Remo, Floridi, Alessandro, Ambesi-Impiombato, Francesco Saverio, Curcio, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139799/
https://ncbi.nlm.nih.gov/pubmed/24979136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150711555
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