In vivo dopaminergic and serotonergic dysfunction in DCTN1 gene mutation carriers

INTRODUCTION: We have used positron emission tomography (PET) to assess dopaminergic and serotonergic terminal density in three subjects carrying a mutation in the DCT1 gene, two clinically affected with Perry syndrome. METHODS: All subjects had brain imaging using 18F-6-fluoro-L-dopa (FDOPA, dopami...

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Main Authors: Felicio, Andre C., Dinelle, Katherine, Agarwal, Pankaj A., McKenzie, Jessamyn, Heffernan, Nicole, Road, Jeremy D., Appel-Cresswell, Silke, Wszolek, Zbigniew K., Farrer, Matthew J., Schulzer, Michael, Sossi, Vesna, Stoessl, A. Jon
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139463/
https://ncbi.nlm.nih.gov/pubmed/24797316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25893
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