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Cell Type Specific Spatial and Functional Coupling Between Mammalian Brain Kv2.1 K(+) Channels and Ryanodine Receptors

The Kv2.1 voltage-gated K(+) channel is widely expressed throughout mammalian brain where it contributes to dynamic activity-dependent regulation of intrinsic neuronal excitability. Here we show that somatic plasma membrane Kv2.1 clusters are juxtaposed to clusters of intracellular ryanodine recepto...

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Autors principals: Mandikian, Danielle, Bocksteins, Elke, Parajuli, Laxmi Kumar, Bishop, Hannah I., Cerda, Oscar, Shigemoto, Ryuichi, Trimmer, James S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139460/
https://ncbi.nlm.nih.gov/pubmed/24962901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23641
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