Loss of estrogen-mediated immunoprotection underlies female gender bias in experimental Crohn’s-like ileitis

The incidence and severity of Crohn’s disease (CD) are increased in female patients. Using SAMP1/YitFc (SAMP) mice, a spontaneous model of chronic intestinal inflammation that displays histologic and pathogenic similarities to human CD, we investigated the potential mechanism(s) contributing to sex...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Goodman, Wendy A., Garg, Rekha R., Reuter, Brian K., Mattioli, Benedetta, Rissman, Emilie F., Pizarro, Theresa T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139459/
https://ncbi.nlm.nih.gov/pubmed/24621993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.15
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky