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Intranasal Delivery of Influenza rNP Adjuvanted with c-di-AMP Induces Strong Humoral and Cellular Immune Responses and Provides Protection against Virus Challenge

There is a critical need for new influenza vaccines able to protect against constantly emerging divergent virus strains. This will be sustained by the induction of vigorous cellular responses and humoral immunity capable of acting at the portal of entry of this pathogen. In this study we evaluate th...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Sanchez, Maria Victoria, Ebensen, Thomas, Schulze, Kai, Cargnelutti, Diego, Blazejewska, Paulina, Scodeller, Eduardo A., Guzmán, Carlos A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139298/
https://ncbi.nlm.nih.gov/pubmed/25140692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104824
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