Relationship between a Common Variant in the Fatty Acid Desaturase (FADS) Cluster and Eicosanoid Generation in Humans

Dramatic shifts in the Western diet have led to a marked increase in the dietary intake of the n-6 polyunsaturated fatty acid (PUFA), linoleic acid (LA). Dietary LA can then be converted to arachidonic acid (ARA) utilizing three enzymatic steps. Two of these steps are encoded for by the fatty acid d...

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Hlavní autoři: Hester, Austin G., Murphy, Robert C., Uhlson, Charis J., Ivester, Priscilla, Lee, Tammy C., Sergeant, Susan, Miller, Leslie R., Howard, Timothy D., Mathias, Rasika A., Chilton, Floyd H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Lipids
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139254/
https://ncbi.nlm.nih.gov/pubmed/24962583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.579557
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