Relationship between a Common Variant in the Fatty Acid Desaturase (FADS) Cluster and Eicosanoid Generation in Humans

Dramatic shifts in the Western diet have led to a marked increase in the dietary intake of the n-6 polyunsaturated fatty acid (PUFA), linoleic acid (LA). Dietary LA can then be converted to arachidonic acid (ARA) utilizing three enzymatic steps. Two of these steps are encoded for by the fatty acid d...

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Main Authors: Hester, Austin G., Murphy, Robert C., Uhlson, Charis J., Ivester, Priscilla, Lee, Tammy C., Sergeant, Susan, Miller, Leslie R., Howard, Timothy D., Mathias, Rasika A., Chilton, Floyd H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Lipids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139254/
https://ncbi.nlm.nih.gov/pubmed/24962583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.579557
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