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Fish Oil and Fenofibrate Prevented Phosphorylation-dependent Hepatic Sortilin 1 Degradation in Western Diet-fed Mice

Obesity and diabetes are associated with hepatic triglyceride overproduction and hypertriglyceridemia. Recent studies have found that the cellular trafficking receptor sortilin 1 (Sort1) inhibits hepatic apolipoprotein B secretion and reduces plasma lipid levels in mice, and its hepatic expression w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Jibiao, Bi, Lipeng, Hulke, Michelle, Li, Tiangang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139250/
https://ncbi.nlm.nih.gov/pubmed/24986865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548933
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