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Insulin Resistance Induces Posttranslational Hepatic Sortilin 1 Degradation in Mice
Insulin promotes hepatic apolipoprotein B100 (apoB100) degradation, whereas insulin resistance is a major cause of hepatic apoB100/triglyceride overproduction in type 2 diabetes. The cellular trafficking receptor sortilin 1 (Sort1) was recently identified to transport apoB100 to the lysosome for deg...
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| I publikationen: | J Biol Chem |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4416856/ https://ncbi.nlm.nih.gov/pubmed/25805502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.641225 |
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