Anamorsin, a Novel Caspase-3 Substrate in Neurodegeneration

Activated caspases play a central role in the execution of apoptosis by cleaving endogenous substrates. Here, we developed a high throughput screening method to identify novel substrates for caspase-3 in a neuronal cell line. Critical steps in our strategy consist of two-dimensional electrophoresis-...

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Detalhes bibliográficos
Main Authors: Yun, Nuri, Lee, Young Mook, Kim, Chiho, Shibayama, Hirohiko, Tanimura, Akira, Hamanaka, Yuri, Kanakura, Yuzuru, Park, Il-Seon, Jo, Areum, Shin, Joo-Ho, Ju, Chung, Kim, Won-Ki, Oh, Young J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139231/
https://ncbi.nlm.nih.gov/pubmed/24973211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.552679
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