Alternative Intronic Polyadenylation Generates the Interleukin-6 Trans-signaling Inhibitor sgp130-E10

Interleukin (IL)-6 signals via a receptor complex composed of the signal-transducing β-receptor gp130 and the non-signaling membrane-bound or soluble IL-6 receptor α (IL-6R, sIL-6R), which is referred to as classic and trans-signaling, respectively. IL-6 trans-signaling is functionally associated wi...

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Главные авторы: Sommer, Jan, Garbers, Christoph, Wolf, Janina, Trad, Ahmad, Moll, Jens M., Sack, Markus, Fischer, Rainer, Grötzinger, Joachim, Waetzig, Georg H., Floss, Doreen M., Scheller, Jürgen
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139227/
https://ncbi.nlm.nih.gov/pubmed/24973212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.560938
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